Table 1. ACGIH data set about 18 carcinogenic substances which are classified by EU in Carc. Cat. 1-2-3 (R 45 - R49 - R40) and for which the Unit Risk by US-EPA is available.

 

Substance name

 

C.A.S.

TLV- TWA
[ACGIH,1998] ppm mg/m3

 

Year

Carc.

Class

TLV-basis

Critical Effect(s)

U.S.EPA
**Unit Risk (per1m g/m3)

1,2-dichloroethane

107-06-2

10

40

1996

Liver necrosis

2.6 E-05

1,3-butadiene

106-99-0

2

4.4

1994

A2

Cancer

2.8 E-04

Acetaldehyde

75-07-0

25*

45

1993

A3

Irritation

2.2 E-06

Acrylonitrile

107-13-1

2

4.3

1984

A2

Cancer

6.8 E-05

Benzene

71-43-2

0.5

1.6

1997

A1

Cancer

8.3 E-06

Beryllium

7440-41-7

0.002

1997

A1

Cancer, berylliosis

2.4 E-03

Carbon tetrachloride

56-23-5

5

31

1996

A2

Liver, Cancer

1.5 E-05

Chloroform

67-66-3

10

49

1996

A3

CNS,CVS,liver, kidney, reprod.ve

2.3 E-05

Dichloromethane

75-09-2

50

174

1996

A3

CNS Anoxia

4.7 E-07

Dichloromethyl-ether

542-88-1

0.001

1981

A1

Cancer (lung)

6.2 E-02

Epichlorohydrin

106-89-8

0.5

1.9

1997

A3

Irritation,liver,
kidney

1.2 E-06

Formaldehyde

50-00-0

0.3*

0.37

1992

A3

Irritation, Cancer

1.3 E-05

Heptachlor

76-44-8

0.05

1994

A3

CNS, liver, blood

1.3 E-03

Heptachlor epoxide

1024-57-3

0.05

1994

A3

CNS, liver, blood

2.6 E-03

Hexachlorobenzene

118-74-1

0.025

1997

A3

Liver,metabolic disorders

4.6 E-04

P,pdichlorodiphenyl- trichlorethane (DDT)

50-29-3

1

1996

A3

Seizures, liver

9.7 E-05

Propilene oxide

75-56-9

20

48

1996

A3

Irritation,CNS

3.7 E-06

Toxaphene

8001-35-2

0.5

1996

A3

Seizures, liver

3.2 E-04